We have discussed antibody humanisation with Olivier Léger. He is an expert in antibody engineering with over 25 years' experience in the field.
Published on 2017-10-02 UpStream Process
Here we discuss about the feasibility to develop a CHO cell line based on retroviral vectors for therapeutic protein projects.
Published on 2017-06-12 Downstream Process
Here we discuss the reasons why a membrane chromatography step might be beneficial in your protein purification process.
Using continuous chromatography to improve process performance and debottleneck bioproduction capacity
Published on 2017-05-12 Downstream Process
In this article, Vincent Monchois, Director of Strategic Projects at Novasep, our CMO partner, explains why integration of continuous chromatography could help the biopharma industry overcome the challenges of increasing capacities and decreasing manufacturing costs.
Published on 2017-03-30 Analytics
In this third article of our series on QC, we are sharing our thoughts on the best way for biotech companies to address analytical development for characterisation of their biotherapeutic candidate at preclinical and clinical stages.
What methods to use for glycan characterisation of your antibody and protein products during process development?
Published on 2017-03-02 Analytics
In this second article of our series on QC development for biotherapeutics, our partner PROTEODYNAMICS, an expert company in glycan analysis and protein characterisation, gives a review of the relevant methods to characterise the glycosylation of your biotherapeutic candidates.
Published on 2017-01-25 Analytics
We are starting a series of articles addressing the question of QC development for biotherapeutic projects and have asked IDBiotech, which specialises in ELISA development, to explain why the quantification of HCPs is a key point to consider in CMC strategy.
We have tested the MEP HyperCel™ Chromatography Sorbent from Pall as a capture step for a polyclonal antibody
Published on 2016-10-13 Downstream Process
What you will read about: our evaluation of the MEP HyperCel™ sorbent as a non-protein A capture step for polyclonal antibodies
Published on 2016-09-19 UpStream Process
What you will read about: Despite a few flaws, P. pastoris has key advantages that make it one of the systems of choice for the production of certain types of protein.
Published on 2016-02-16 UpStream Process
What you will read about: our opinion on the best system to use for production of your MAb candidates for POC studies.